Laboratory of Smart Molecule
- Research Theme
- Creation of light-controlled molecular machines
- Research Keywords
molecular machine, motor protein, photochromic compound, azobenzene, liquid crystal, self-organization, inter-molecular interaction, organic synthesis, nano bio-machine, single molecular measurement, chirality
Staff
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TAMAOKI Nobuyuki Professor
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PADINHARE KAYAKALI Hashim Assistant Professor
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AMMATHNADU SUDHAKAR Amrutha Assistant Professor
Overview of Research and Education
Research Contents: Although living things consist of molecules as non-living things do, we smartly sense and judge surroundings and do the action by ourselves. It is still important topic in the present science to envisage what is special and what is not special in the molecular level for the outwardly special living things in comparison with non-living things. We think that constructing new artificial molecular systems with various information functions which are realized in the living systems will contribute to the deep understanding of the living things. This is the opposite way of the usual biology where we observe living things itself directly.
Laboratory of Smart Molecule (pdf)
Practical Subjects
Charge
- Charge (US):
School of Science, Biological Science course (Macromolecular Functions), Collaborative Laboratories - Charge (GS):
Graduate School of Life Science, Division of Life Science, Transdisciplinary Life Science Course, Biomaterials Science
Contact
- Address
- 〒001-0020
Research Institute for Electronic Science, Hokkaido University
Kita20, Nishi10, Kita-ku, Sapporo - Phone
- 011-706-9356
- Fax
- 011-706-9357
- tamaoki*es.hokudai.ac.jp(Please replace*with @ when sending e-mail.)
Representative Publications
Noushaba Nusrat Mafy, Kazuya Matsuo, Shota Hiruma, Ryota Uehara and Nobuyuki Tamaoki, “Photoswitchable CENP-E inhibitor enabling the dynamic control of chromosome movement and mitotic progression”, J. Am. Chem. Soc., 2020, 142(4), 1763-1767
Noushaba Nusrat Mafy, Yuna Kim, Reji Thomas, Takehito Akasaka, and Nobuyuki Tamaoki, “Molecular Crankshaft Effect Converting Piston-like Molecular Motion to Continuous Rotation of Macro Objects”, ACS Appl. Mater. Interfaces, 2019, 11 (16), 15097-15102
Yuna Kim, Ken’ichi Aoki, Masaya Fujioka, Junji Nishii, and Nobuyuki Tamaoki, “Pressure-Induced Transition of Bisamide Substituted Diacetylene Crystals from Non-Photopolymerizable to Photopolymerizable State”, ACS Appl. Mater. Interfaces, 2018, 10(42), 36407-36414
K. R. Sunil Kumar , Takashi Kamei , Tuyoshi Fukaminato , and Nobuyuki Tamaoki, “Complete ON/OFF Photoswitching of the Motility of a Nanobiomolecular Machine”, ACS Nano,2014, 8(5), 4157-4165
Nishad Perur, Masao Yahara, Takashi Kamei, Nobuyuki Tamaoki, “A non-nucleoside triphosphate powering kinesin-microtubule motility with photo-tunable velocity”, Chem. Commun, 2013, 49, 9935-9937