Laboratory

Laboratory of Smart Molecule

Research Theme
Creation of light-controlled molecular machines
Research Keywords

molecular machine, motor protein, photochromic compound, azobenzene, liquid crystal, self-organization, inter-molecular interaction, organic synthesis, nano bio-machine, single molecular measurement, chirality

Staff

Overview of Research and Education

Research Contents: Although living things consist of molecules as non-living things do, we smartly sense and judge surroundings and do the action by ourselves. It is still important topic in the present science to envisage what is special and what is not special in the molecular level for the outwardly special living things in comparison with non-living things. We think that constructing new artificial molecular systems with various information functions which are realized in the living systems will contribute to the deep understanding of the living things. This is the opposite way of the usual biology where we observe living things itself directly.

Laboratory of Smart Molecule (pdf)

Practical Subjects
Bio
Chem
Phy
Math

Charge

Contact

Address
〒001-0020
Research Institute for Electronic Science, Hokkaido University
Kita20, Nishi10, Kita-ku, Sapporo
Phone
011-706-9356
Fax
011-706-9357
Email
tamaoki*es.hokudai.ac.jp(Please replace*with @ when sending e-mail.)

Representative Publications

Noushaba Nusrat Mafy, Kazuya Matsuo, Shota Hiruma, Ryota Uehara and Nobuyuki Tamaoki, “Photoswitchable CENP-E inhibitor enabling the dynamic control of chromosome movement and mitotic progression”, J. Am. Chem. Soc., 2020, 142(4), 1763-1767

Noushaba Nusrat Mafy, Yuna Kim, Reji Thomas, Takehito Akasaka, and Nobuyuki Tamaoki, “Molecular Crankshaft Effect Converting Piston-like Molecular Motion to Continuous Rotation of Macro Objects”, ACS Appl. Mater. Interfaces, 2019, 11 (16), 15097-15102

Yuna Kim, Ken’ichi Aoki, Masaya Fujioka, Junji Nishii, and Nobuyuki Tamaoki, “Pressure-Induced Transition of Bisamide Substituted Diacetylene Crystals from Non-Photopolymerizable to Photopolymerizable State”, ACS Appl. Mater. Interfaces, 2018, 10(42), 36407-36414

K. R. Sunil Kumar , Takashi Kamei , Tuyoshi Fukaminato , and Nobuyuki Tamaoki, “Complete ON/OFF Photoswitching of the Motility of a Nanobiomolecular Machine”, ACS Nano,2014, 8(5), 4157-4165

Nishad Perur, Masao Yahara, Takashi Kamei, Nobuyuki Tamaoki, “A non-nucleoside triphosphate powering kinesin-microtubule motility with photo-tunable velocity”, Chem. Commun, 2013, 49, 9935-9937

Refer to HOKKAIDO UNIVERSITY RESEARCHERS DIRECTORY
(https://researchers.general.hokudai.ac.jp/profile/en.-bdJxYR-caVkAY3J7h.JZw==.html)