Prof. Asahara and Dr. Nakamichi (Tokyo Medical and Dental University) with Dr. Nonoyama (Faculty of Advanced Life Science, Hokkaido University) and Scripps Research Group have discovered that the mechano-sensor PIEZO1 in tendon cells enhances the athletic performance of individuals. This research result has been published on Science Translational Medicine.
Points in the report
- We analyzed the function of the mechanical stimulus-responsive calcium channel receptor PIEZO1 in tendon cells.
- Inducing PIEZO1 constitutive activity in tendon cells has been shown in mouse experiments to improve individual athletic performance.
- It was clarified that the prevalence of the constitutively active gene polymorphism of PIEZO1 is high in Jamaican sprinters.
- It can be expected to be applied to improve athletic ability and healthy life.
Please see the following press release for the detail.