Aggregate dysfunction and subsequent cell fate using a light inactivation method

Akira Kitamura, a lecturer at Faculty of Advanced Life Science, Hokkaido University, and his colleagues have successfully developed an optogenetic method to localize monomeric red fluorescent protein (SuperNova-Red) to stress granules in cells and then irradiate them with light, thereby inducing dysfunction of stress granules with controlling spatiotemporal manner.

Original article: Stress Granule Dysfunction via Chromophore-Associated Light Inactivation