NONOYAMA TakayukiAssociate Professor
- Laboratory
- Laboratory of Soft & Wet Matter
- Research Theme
- Hybridization of Bioceramics & Robust Gel, Thermo-active hydrogel
- Research Keywords
Double Network gel, Phase Separation, Bioceramics
Overview of Research
(1) Cartilage tissues are a single-use tissue like an eraser that can not be expected to cure naturally if it is degraded or damaged due to injury, disease, aging, etc. Although the current radical treatment is artificial joint replacement, which replaces hard materials, not only normal tissues have to be resected, but also there are clinical problems such as loosening in long-term use. Therefore, there is a strong demand for developments of next-generation artificial cartilage and ultimate tissue reconstruction. We have developed a robust gel that satisfies the physical properties required for artificial cartilage, and are further developing technology to firmly fix it in proper place of defect for a long time. Focusing on the fact that natural cartilage tissue is in continuous contact with bone tissue, when the inorganic main component of bone is combined with gel, bone regeneration can penetrate inside the gel and achieve non-toxic and strong adhesion. We are also creating high-strength composite materials by combining bioceramics and hydrogel.
(2) General polymer materials behave as a hard glassy state below glass-transition temperature (Tg), and change to a soft rubbery state above Tg. We are creating temperature-responsive active materials that are more than 1000 times harder at high temperatures, which is the reverse thermal behavior of general polymers. This material is extremely easy to make, using very inexpensive and non-toxic chemicals, and can be hardened repeatedly. This material is intended to be used as a smart protector responsive to heat and a heat absorbing material that absorbs heat from sunlight and reduces the temperature rise in the room.
Charge
- School of Science:
Biological Science course (Macromolecular Functions), Core Laboratories - Graduate School of Life Science:
Division of Soft Matter, Soft Matter Materials Science
Message
We believe that discoveries of new phenomena and materials are often found by chance in various experiments. Our laboratory emphasizes on students’ flexible and freewheeling ideas. Let’s make your ideas real in our lab.
Representative Publications
Refer to HOKKAIDO UNIVERSITY RESEARCHERS DIRECTORY
Note
<Office Hour>
– Time: Anytime during the lecture period
– Place: Frontier-AMLS, 3F
Please contact in advance by E-mail.
E-mail: nonoyama[at]sci.hokudai.ac.jp
Affiliation
- Faculty of Advanced Life Science, Department of Advanced Transdisciplinary Sciences, Soft & Wet Matter Science
- Frontier Research Center for Advanced Material and Life Science, Global Collaboration Unit, Soft Matter Collaborative Research Unit