Study clarified that shorter sleep time is associate with lower α-defensin secretion and further induces disruption of the intestinal microbiota along with low production of short-chain fatty acids, showing previously unknown relationship between the intestine and brain.
This research topic is related to the sustainable development goals (SDGs);
3. GOOD HEALTH AND WELL-BEING
8. DECENT WORK AND ECONOMIC GROWTH
Yu Shimizu, Ryodai Yamamura, Yuki Yokoi, Tokiyoshi Ayabe, Shigekazu Ukawa, Koshi Nakamura, Emiko Okada, Akihiro Imae, Takafumi Nakagawa, Akiko Tamakoshi, and Kiminori Nakamura. Shorter sleep time relates to lower human defensin 5 secretion and compositional disturbance of the intestinal microbiota accompanied by decreased short-chain fatty acid production 2023. 15: 2190306. doi: 10.1080/19490976.2023.2190306