1. Uehara R., Nozawa R., Tomioka A., Petry S., Vale R.D., Obuse C., Goshima G.
    The augmin complex plays a critical role in spindle microtubule generation for mitotic progression and cytokinesis in human cells.
    Proc.Natl.Acad.Sci. USA., 106, 6998-7003 (2009).
  2. Hanyu Y., Imai K, K., Kawasaki,Y., Nakamura T., Nakaseko Y., Nagao K., Kokubu A., Ebe M., Fujisawa A., Hayashi T., Obuse C., Yanagida M.
    S. pombe cell division cycle under limited glucose requires Ssp1 kinase, the putative CaMKK, and Sds23, a PP2A-related phosphatase inhibitor.
    Genes to Cells, 14, 539-54 (2009).
  3. Perpelescu M., Nozaki N., Obuse C., Yang H., Yoda Y.
    Active establishment of centromeric CENP-A chromatin by RSF complex
    J.Cell Biol., 185, 397-407 (2009).
  4. Suizu F., Hiramuki Y., Okumura F., Matsuda M., Okumura J. A., Hirata N., Narita M., Kohno T., Yokota J., Bohgaki M., Obuse C., Hatakeyama S., Obata T., Noguchi M.
    The E3 ligase TTC3 facilitates ubiquintination and degradation of phosphorylated Akt
    Dev.Cell., 17, 800-10 (2009).
  5. KiyomitsuT., Iwasaki O., Obuse C., Yanagida M.
    Inner centromere formation requires hMis14, a trident kinetochore protein that specifically recruits HP1 to human chromosomes
    J Biol Chem., 285, 9858-67 (2009).
  6. Osakabe, A., Tachiwana, H., Matsunaga, T., Shiga, T., Nozawa, R., Obuse, C., Kurumizaka, H.
    Nucleosome Formation Activity of Human Somatic Nuclear Autoantigenic Sperm Protein (sNASP)
    J Biol Chem., 285, 11913-21.
  7. Suehara Y., Kikuta K., Nakayama R., Fujii K., Ichikawa H., Shibata T., Seki K., Hasegawa T., Gotoh M., Tochigi N., Shimoda T., Shimada Y., Sano T., Beppu Y., Kurosawa H., Hirohashi S., Kawai A., Kondo T.
    Anatomic site-specific proteomic signatures of gastrointestinal stromal tumors.
    Proteomics Clin. Appl., 3, 584-96 (2009).
  8. Suehara Y., Kikuta K., Nakayama R., Tochigi N., Seki K., Ichikawa H., Fujii K., Hasegawa T., Shimoda T., Kurosawa H., Chuman H., Beppu Y., Kawai A., Hirohashi S., Kondo T.
    GST-P1 as a histological biomarker of synovial sarcoma revealed by proteomics.
    Proteomics Clin. Appl., 3, 623-34 (2009).
  9. Kawase H., Fujii K., Miyamoto M., Kubota K. C., Hirano S., Kondo S., Inagaki F.
    Differential LC-MS-based proteomics of surgical human cholangiocarcinoma tissues.
    J Proteome Res., 8, 4092-103 (2009).
  10. Kawamura T., Nomura M., Tojo H., Fujii K., Hamasaki H., Mikami S., Bando Y., Kato H., Nishimura T.
    Proteomic analysis of laser-microdissected paraffin-embedded tissues: (1) Stage-related protein candidates upon non-metastatic lung adenocarcinoma.
    J Proteomics., 73, 1089-99( 2010)
  11. Nishimura T., Nomura M., Tojo H., Hamasaki H., Fukuda T., Fujii K., Mikami S., Bando Y., Kato H.
    Proteomic analysis of laser-microdissected paraffin-embedded tissues: (2) MRM assay for stage-related proteins upon non-metastatic lung adenocarcinoma.
    J Proteomics., 73, 1100-10( 2010)
  12. Fujii K., Nakamura S., Takahashi K., Inagaki F.
    Systematic characterization by mass spectrometric analysis of phosphorylation sites in IRF-3 regulatory domain activated by IKK-i.
    J Proteomics., 73, 1196-203( 2010)
  13. Matsushita T., Sadamoto R., Ohyabu N., Nakata H., Fumoto M., Fujitani N., Takegawa Y., Sakamoto T., Kurogochi M, Hinou H., Shimizu H., Ito T., Naruchi K., Togame H., Takemoto H., Kondo H., Nishimura S.-I.
    “Functional neoglycopeptides: synthesis and characterization of a new class of MUC1 glycoprotein models having core 2-based O-glycan and complex-type N-glycan chains.”
    Biochemistry., 48, 11117-33( 2009)
  14. Tano C., Son S.-H. , Furukawa J.-i., Furuike T., Sakairi N..
    Enantiomeric separation by MEKC using dodecyl thioglycoside surfactants: importance of an equatorially oriented hydroxy group at C-2 position in separation of dansylated amino acids
    Electrophoresis., 30 (15), 2743-6 (2009).
  15. SonS.-H. , Yanagiya N., Furukawa J.-i., Sakairi N.,
    Intramolecular Glycosylation Approach toward Constructing the Macrocyclic Structure of Resin Glycosides
    Synlett, 2957-60 (2009).
  16. Amano M., Yamaguchi M., Takegawa Y., Yamashita T., Terasima M., Furukawa J.-i., Miura Y., Shinohara Y., Iwasaki N., Minami A., Nishimura S.-I.
    Threshold in Stage Specific Embryonic Glycotypes Uncovered by a Full Portrait of Dynamic N-Glycan Expression during Cell Differentiation.
    Mol. Cell. Proteomics., 9, 523-37 (2010) .
  17. Kimura A., Tandang M.-R., Fukuda T., Cabanos C., Takegawa Y., Amano M., Nishimura S.-I., Matsumura Y., Maruyama N., Utsumi S.
    Carbohydrate moieties contribute significantly to the excellent physicochemical properties of French bean 7S globulin phaseolin.
    J. Agric. Food. Chem., 58, 2923-30 (2010).
  18. Takeda, K., Yoshida, Y., Kikuchi, S., Nagao, K., Kokubu, A., Pluskal, T., Villar-Briones, A., Nakamura, T., Yanagida, M.
    Synergistic Roles of Proteasome and Autophagy for Mitochondrial Maintenance and Chronological Life Span.
    Proc. Natl. Acad. Sci. USA., 107, 3540-5 (2010).
  19. Kimura A., Tandang-Silvas M.R.G., Fukuda T.,Cabanos C.,† Takegawa Y., Amano M., Nishimura S.-I., Matsumura Y., Utsumi S., and Maruyama N.
    Carbohydrate Moieties Contribute Significantly to the Physicochemical Properties of French Bean 7S Globulin Phaseolin
    J. Agric. Food Chem., 58, 2923-30 (2010).


  1. 清光智美、小布施力史、柳田充弘
    ブリンキン-紡錘体形成チェックポイントと微小管結合に必須なキネトコア蛋白質.染色体サイクル(正井久雄・升方久夫・釣本敏樹・仁木宏典・篠原 彰 編)
    蛋白質・核酸・酵素(増刊), 54, 421-6( 2009).
  2. 野澤竜介、小布施力史
    ヘテロクロマチン結合因子とその機能 細胞核-遺伝情報制御と疾患
    実験医学(増刊), 27,123-30( 2009).
  3. 長尾恒治、野澤竜介、小布施力史
    細胞工学(別冊), 81-90( 2009).
  4. 藤井清永、中野智世、碓井史彦、板東泰彦、稲垣冬彦、西村俊秀
    質量分析, 57, 317-325( 2009).
  5. 天野麻穂
    臨床化学, 39, 81( 2010).



  1. November 2009
    Sapporo, Japan
    International mini-symposium on chromosome biology : Centromeres to telomeres and te chromatin between
    An HP1 binding protein POGZ has pivotal role in mitotic chromosome organization in human cells
    Obuse Chikashi.
  2. October 2009
    Sapporo, Japan
    The 1st Hokkaido University-Academia Sinica Joint Symposium
    Unambiguous identification of multiple O-glycosylation sites using electron capture dissociation with various electron energies
    Takegawa Y.
  3. July 2009
    Vienna, Austria
    15th European Carbohydrate Symposium
    Comparative Glycomics
    Maho Amano.
  4. October 2009
    Sapporo, Japan
    The 1st Hokkaido University-Academia Sinica Joint Symposium and The 7th Symposium For Future Drug Discovery and Medical Care
    Comparative Glycomics
    Maho Amano.
  5. December 2009
    San Juan, Puerto Rico, USA
    20th International Symposium on Glycoconjugates
    Quantitative Glycomics During Cellular Differentiation
    Maho Amano.


  1. 2009年10月
  2. 2009年11月
  3. 2009年7月
  4. 2009年7月
  5. 2010年2月
  6. 2009年9月
    ブルカー・ダルトニクス ユーザーミーティング2009


  1. 2010/3/4 (特願2010-048003)
  2. 2010/3/4 (特願2010-048004)
  3. 2009, 7598372 (US)
    Synthesis of core sugar chain structures of asparagines-linked glycoprotein
    発明者:Nishimura, S.-I., Takegawa, Y.
  4. (特願2009-220893)
  5. (特願2009-229046)