Laboratory

Lipid Biofunction Section

Research Keywords

Sphingosine-1-phosphate, Ceramide, Sphingomyelin, Sphingolipids, Altzheimer’s disease, Exosome, Epidermal barrier, Signal transduction, Atopic eczema, Intestinal absorption of dietary sphingolipids

Staff

Overview of Research and Education

Sphingolipids are a class of lipids containing backbone of long-chain bases, and characterized by various molecules of ceramides, sphingomyelin, and glycosphingolipids. Sphingolipids are a major component of membrane lipids of cells together with glycerophospholipids and cholesterols. In addition, sphingosine-1-phosphate is known to be a signal-transducing molecule in sphingolipids. In our laboratory, we have studied biological mechanism of sphingolipids for epidermal barrier, itch nerve extension, and disease-related functions of sphingolipids for diseases such as Altzheimer’s disease (AD) and metabolic syndrome. We are also trying a developmental study of an advanced material from sphingolipids.

Charge

Contact

Address
Kit 21, nishi 11, Kita-ku, Sapporo, Hokkaido, 001-0021, Japan
Phone
81-(0)-11-706-9001
Fax
81-(0)-11-706-9024
Email
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