研究室

ソフト&ウェットマター研究室

ソフトマテリアルから、生物の優れた機能に挑む
研究テーマ
生物の構造をヒントに、優れた機能を有する高分子ゲルの創製と応用
研究キーワード

ソフト＆ウェットマター、高分子ゲル、ダブルネットワークゲル、金属より丈夫なゲル、自己修復ゲル、自己成長ゲル、接着するゲル、熱で強靭化ゲル、低摩擦ゲル、超潤滑ゲル、色が変化するゲル、海で接着するゲル、人工軟骨、細胞足場ゲル

スタッフ

研究・教育内容

(1)本研究室はソフトマターである「ゲル」を取り扱っている。柔らかくて大変形することに加えて，生体のような優れた機能，特に力学機能を有する高分子ゲルを創製し，その機能発現の原理を解明すると共に，ゲルを軟骨などの生体代替軟組織へ応用することを目指している。また，これらのゲル研究の成果を他のソフトマター材料へ拡張し，工業材料へ応用することも目的にしている。

代表的な研究テーマは
１）高強度・高靭性ゲル・エラストマーのデザインと創製，
２）ソフトマターのダイナミックスと破壊・疲労機構の解明，
３）水中接着性ゲルのデザイン・創製とその機構解明，
４）高靭性ソフト複合材料の創製と破壊機構の解明，
５）筋肉のように鍛えると強くなるゲルのデザインと創製，
６）バイオミネラルゼーションによるソフトセラミックスの創製，
７）高温でガラス化するソフトマテリアルの創製，
８）ダブルネットワークゲルによる高分子鎖の力学解析

(2)次世代物質生命科学研究センター・ソフトマター国際連携ユニットと連携し、ソフトマターの新規材料開発に関する理論、特に力学機能の発現原理の解明を行う。

ソフト&ウェットマター研究室 (pdf)

担当学部・大学院

お問合せ

研究室所在地
〒001-0021
札幌市北区北21条西11丁目
北海道大学北キャンパス総合研究棟2号館（次世代物質生命科学研究棟）4階4-13
電話番号
011-706-9011
Fax番号
011-706-9011
Email
gong*sci.hokudai.ac.jp（*を半角@に変えて入力ください）

代表的な研究業績

Original papers

  1. J. P. Gong, Y. Katsuyama, T. Kurokawa, Y. Osada, “Double Network Hydrogels with Extremely High Mechanical Strength”, Advanced Materials, 15, 1155-1158 (2003). (top 1% paper)
  2. Md. A. Haque, G. Kamita, T. Kurokawa, J. P. Gong, “Unidirectional Alignment of Lamellar Bilayer in Hydrogel: One-Dimensional Swelling, Anisotropic Modulus, and Stress/Strain Tunable Structural Color”, Advanced Materials, 22, 5110-5114 (2010).
  3. Md. A. Haque, T. Kurokawa, G. Kamita, J. P. Gong, “Lamellar Bilayers as Reversible Sacrificial Bonds To Toughen Hydrogel: Hysteresis, Self-Recovery, Fatigue Resistance, and Crack Blunting “, Macromolecules, 44, 8916-8924 (2011).
  4. T. L. Sun, T. Kurokawa, S. Kuroda, A. B. Ihsan, T. Akasaki, K. Sato, M. A. Haque, T. Nakajima, J. P. Gong “Physical hydrogels composed of polyampholytes demonstrate high toughness and viscoelasticity”, Nature Materials, 12, 932-937 (2013). (top 1% paper)
  5. F. Luo, T. L. Sun, T. Nakajima, T. Kurokawa, Y. Zhao, K. Sato, A. B. Ihsan, X. F. Li, H. L. Guo, J. P. Gong, “Oppositely Charged Polyelectrolytes Form Tough, Self-healing and Rebuildable Hydrogels”, Advanced Materials, 27, 2722-2727 (2015). (top 1% paper)
  6. H. J. Zhang, T. L. Sun, A. K. Zhang, Y. Ikura, T. Nakajima, T. Nonoyama, T. Kurokawa, O. Ito, H. Ishitobi, J. P. Gong, “Tough Physical Double-Network Hydrogels Based on Amphiphilic Triblock Copolymers,” Advanced Materials, 28, 4884-4890 (2016). (top 1% paper)
  7. T. Matsuda, T. Nakajima, Y. Fukuda, W. Hong, T. Sakai, T. Kurokawa, U. Chung, J. P. Gong, Yielding Criteria of Double Network Hydrogels, Macromolecules, 49(5), 1865-1872 (2016).
  8. T. L. Sun, F. Luo, W. Hong, K. Cui, Y. Huang, H. Zhang, D. R. King, T. Kurokawa, T. Nakajima, J. P. Gong, Bulk Energy Dissipation Mechanism for the Fracture of Tough and Self-Healing Hydrogels, Macromolecules, 50(7), 2923-2931 (2017).
  9. K. Cui, T. L. Sun, X. Liang, K. Nakajima, Y. N. Ye, L. Chen, T. Kurokawa, J. P. Gong, Multiscale Energy Dissipation Mechanism in Tough and Self-Healing Hydrogels, Physical Review Letters (2018).
  10. P. Rao, T. L. Sun, L. Chen, R. Takahashi, G. Shinohara, H. Guo, D. R. King, T. Kurokawa, J. P. Gong, Tough Hydrogels with Fast, Strong, and Reversible Underwater Adhesion Based on a Multi-Scale Design, Advanced Materials, 30(32), 1801884 (2018).
  11. T. I. Mredha, T. Nonoyama, T. Nakajima, Y. Z. Guo, T. Kurokawa, J. P. Gong, “A Facile Method to Fabricate Anisotropic Hydrogels with Perfectly Aligned Hierarchical Fibrous Structures”, Advanced Materials, 30(9), 1704937 (2018).
  12. R. Takahashi, T. L. Sun, Y. Saruwatari, T. Kurokawa, D. R. King, J. P. Gong, “Creating Stiff, Tough, and Functional Hydrogel Composites with Low Melting Point Alloys”, Advanced Materials, 30, 1706885 (2018).
  13. H. Guo, T. Nakajima, D. Hourdet, A. Marcellan, C. Creton, W. Hong, T. Kurokawa, J. P. Gong, Hydrophobic Hydrogels with Fruit-Like Structure and Functions, Advanced Materials, 31(25), 1900702 (2019)
  14. H. Fan, J. Wang, Z. Tao, J. Huang, P. Rao, T. Kurokawa, J. P. Gong, “Adjacent Cationic-Aromatic Sequences Yield Strong Electrostatic Adhesion of Hydrogels in Seawater”, Nature Communications, 10, 5127 (2019).
  15. T. Matsuda, R. Kawakami, R. Namba, T. Nakajima, J. P. Gong, “Mechanoresponsive Self-growing Hydrogels Inspired by Muscle Training”, Science, 363, 504-508 (2019). (top 1% paper)
  16. X. Li, K. Cui, T. L. Sun, L. Meng, C. Yu, L. Li, C. Creton, T. Kurokawa, J. P. Gong, Mesoscale Bicontinuous Networks in Self-healing Hydrogels Delay Fatigue Fracture, Proc. Natl. Acad. Sci. U.S.A., 117(14), 7606-7612 (2020)
  17. T. Nonoyama, Y. W. Lee, K. Ota, K. Fujioka, W. Hong, J. P. Gong, Instant Thermal Switching from Soft Hydrogel to Rigid Plastics Inspired by Thermophile Proteins, Advanced Materials, 32(4), 1905878 (2020).
  18. W. Cui, D. R. King, Y. Huang, L. Chen, T. L. Sun, Y. Guo, Y. Saruwatari, C.-Y. Hui, T. Kurokawa, J. P. Gong, Fiber‐Reinforced Viscoelastomers Show Extraordinary Crack Resistance That Exceeds Metals, Advanced Materials, 32(31), 1907180 (2020)
  19. T. Matsuda, R. Kawakami, T. Nakajima, J. P. Gong, “Crack Tip Field of a Double-Network Gel: Visualization of Covalent Bond Scission through Mechanoradical Polymerization”, Macromolecules, 53, 5787-8795 (2020).
  20. C. Yu, H. Guo, K. Cui, X. Li, Y. N. Ye, T. Kurokawa, J. P. Gong, “Hydrogels as Dynamic Memory with Forgetting Ability,” Proc. Natl. Acad. Sci. U.S.A., 117(32), 18962-18968 (2020).
  21. Y. N. Ye, K. Cui, W. Hong, X. Li, Ch. Yu, D. Hourdet, T. Nakajima, T. Kurokawa, J. P. Gong, “Molecular Mechanism of Abnormally Large Nonsoftening Deformation in a Tough Hydrogel”, Proc. Natl. Acad. Sci. U.S.A., 118, e2014694118 (2021).
  22. X. Li, K. Cui, T. Kurokawa, Y. N. Ye, T. L. Sun, C. Yu, C. Creton, J. P. Gong, “Effect of Mesoscale Phase Contrast on Fatigue-Delaying Behavior of Self-Healing Hydrogels”, Science Advances, 7, eabe8210 (2021).
  23. Z. Wang, X. Zheng, T. Ouchi, T. B. Kouznetsova, H. K. Beech, S. Av-Ron, T. Matsuda, B. H. Bowser, S. Wang, J. A. Johnson, J. A. Kalow, B. D. Olsen, J. P. Gong, M. Rubinstein, S. L. Craig, “Toughening hydrogels through force-triggered chemical reactions that lengthen polymer strands,” Science, 374, 193-196 (2021).
  24. X. Y. Li, J. P. Gong, “Role of Dynamic Bonds on Fatigue Threshold of Tough Hydrogels,” PNAS, 119(20), e2200678119 (2022).
  25. Z. J. Wang, J. Jiang, Q. Mu, S. Maeda, T. Nakajima, J. P. Gong, “Azo-Crosslinked Double-Network Hydrogels Enabling Highly Efficient Mechanoradical Generation,” J. Am. Chem. Soc. 144, 7, 3154–3161(2022).
  26. Q.-F. Mu, K.-P. Cui, Z. J. Wang, T. Matsuda, W. Cui, H. Kato, S. Namiki, T. Yamazaki, M. Frauenlob, T. Nonoyama, M. Tsuda, S. Tanaka, T. Nakajima, J. P. Gong, “Force-triggered rapid microstructure growth on hydrogel surface for on-demand functions,” Nature Communications, 13, Article number: 6213 (2022).
  27. R. Kiyama, M. Yoshida, T. Nonoyama, T. Sedlačík, H. Jinnai, T. Kurokawa, T. Nakajima, J. P. Gong, “Nanoscale TEM Imaging of Hydrogel Network Architecture,” Advanced Materials, 35(1), 2208902 (2023).
  28. Gumi Wei, Yumeko Kudo, Takahiro Matsuda, Zhi Jian Wang, Qi Feng Mu, Daniel R. King, Tasuku Nakajima, Jian Ping Gong, “Sustainable mechanochemical growth of double-network hydrogels supported by vascular-like perfusion”, Materials Horizons, 2023,10, 4882-4891(2023).
  29. Xueyu Li, Kunpeng Cui, Yong Zheng, Ya Nan Ye, Chengtao Yu, Wenqi Yang, Tasuku Nakajima, Jian Ping Gong, “Role of hierarchy structure on the mechanical adaptation of self-healing hydrogels under cyclic stretching”, Science Advances, 9, 51 (2023).
  30. Yiran Li, Bin Xue, Jiahui Yang, Julong Jiang, Jing Liu, Yanyan Zhou, Junsheng Zhang, Mengjiao Wu, Yuan Yuan, Zhenshu Zhu, Zhi Jian Wang, Yulan Chen, Yu Harabuchi, Tasuku Nakajima, Wei Wang, Satoshi Maeda, Jian Ping Gong, Yi Cao, “Azobenzene as a photoswitchable mechanophore,” Nature Chemistry, 16, 446–455 (2023).

Review papers

  1. J. P. Gong, “Why are double network hydrogels so tough?” Soft Matter, 6, 2583-2590 (2010). (top 1% paper)
  2. Md. A. Haque, T. Kurokawa, J. P. Gong, “Super tough double network hydrogels and their application as biomaterials”, Polymer, 53(9), 1805-1822 (2012). (top 1% paper)
  3. J. P. Gong, “Materials both Tough and Soft”, Science, 344, 161-162 (2014). (top 1% paper)
  4. H. L. Fan, J. P. Gong, “Fabrication of Bioinspired Hydrogels: Challenges and Opportunities,” Macromolecules, 53(8), 2769-2782 (2020). (top 1% paper)
  5. H. L. Fan, J. P. Gong, “Bioinspired Underwater Adhesives”, Advanced Materials, 33(44), 2102983 (2021). (top 1% paper)
  6. R. Long, C.-Y. Hui, J. P. Gong, E. Bouchbinder, “The Fracture of Highly Deformable Soft Materials: A Tale of Two Length Scales”, Annual Review of Condensed Matter Physics, 12(1), 71-94 (2021). (top 1% paper)